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To quickly search the same gene in another data set, click the links from the last column. The locuslink number will be used as query.


No probe set Gene Name Accession LocusLink Symbol Alias Symbols Description CTRL FSK (FSK vs CTRL) FC (FSK vs CTRL) LFC Note Link
1 221961_at chloride channel 7 AW1902081186CLCN7 CLC-7;CLC7;OPTA2 Consensus includes gb:AW190208 /FEA=EST /DB_XREF=gi:6464688 /DB_XREF=est:xl60a12.x1 /CLONE=IMAGE:2679070 /UG=Hs.233789 ESTs 92.38 119.51 1.29 0.84 "all, " HEK293T_Expression Human_ChIP_chip Human_CRE_prediction
2 38069_at chloride channel 7 Z677431186CLCN7 CLC-7;CLC7;OPTA2 " Cluster Incl. Z67743:H.sapiens mRNA for CLC-7 chloride channel protein /cds=(0,2369) /gb=Z67743 /gi=1177439 /ug=Hs.80768 /len=2393 " 606 562.05 -1.08 -1.01 "all, " HEK293T_Expression Human_ChIP_chip Human_CRE_prediction
3 209235_at chloride channel 7 AL0316001186CLCN7 CLC-7;CLC7;OPTA2 "Consensus includes gb:AL031600 /DEF=Human DNA sequence from clone 390E6 on chromosome 16. Contains the 3 part of the CLCN7 gene for chloride channel 7, ESTs, a GSS and four putative CpG islands /FEA=mRNA /DB_XREF=gi:4826481 /UG=Hs.80768 chloride channel 7 /FL=gb:AF224741.1" 396.39 265.55 -1.49 -1.19 "all, " HEK293T_Expression Human_ChIP_chip Human_CRE_prediction

Sample Description:
Primary culture of human pancreatic islet was treated with cAMP agonist forskolin (FSK) and compared with control untreated samples. RNA was extracted using the Qiagen RNeasy kit. Two control and two forskolin treated samples were analyzed.

Microarray Analysis:
Total RNA samples were labeled and hybridized by standard protocol to Affymetrix GeneChip Human Genome U133A 2.0 Array. Array data was analyzed using the dChip software with PM-MM models.

Guidelines for Choosing camp Induced Genes in this Data Set:
The fold change (FC) value is positive for increased expression and negative for decrease expression. There is also a lower bound of fold change (LFC), which is a conservative estimation of the fold change with 90% confidence. For this data set, if a gene was induced by FSK with LFC>=1.3, we consider it as a good camp induced gene and therefore a potential CREB target.