Search results are listed below.
Tip: To
quickly search the same gene in another data set, click the links from the last
column. The locuslink number will be used as query.
| No | probe set | Gene Name | Accession | LocusLink | Symbol | Alias Symbols | Description | CTRL | FSK | (FSK vs CTRL) FC | (FSK vs CTRL) LFC | Note | Link |
| 1 | 221961_at | chloride channel 7 | AW190208 | 1186 | CLCN7 | CLC-7;CLC7;OPTA2 | Consensus includes gb:AW190208 /FEA=EST /DB_XREF=gi:6464688 /DB_XREF=est:xl60a12.x1 /CLONE=IMAGE:2679070 /UG=Hs.233789 ESTs | 92.38 | 119.51 | 1.29 | 0.84 | "all, " | HEK293T_Expression Human_ChIP_chip Human_CRE_prediction |
| 2 | 38069_at | chloride channel 7 | Z67743 | 1186 | CLCN7 | CLC-7;CLC7;OPTA2 | " Cluster Incl. Z67743:H.sapiens mRNA for CLC-7 chloride channel protein /cds=(0,2369) /gb=Z67743 /gi=1177439 /ug=Hs.80768 /len=2393 " | 606 | 562.05 | -1.08 | -1.01 | "all, " | HEK293T_Expression Human_ChIP_chip Human_CRE_prediction |
| 3 | 209235_at | chloride channel 7 | AL031600 | 1186 | CLCN7 | CLC-7;CLC7;OPTA2 | "Consensus includes gb:AL031600 /DEF=Human DNA sequence from clone 390E6 on chromosome 16. Contains the 3 part of the CLCN7 gene for chloride channel 7, ESTs, a GSS and four putative CpG islands /FEA=mRNA /DB_XREF=gi:4826481 /UG=Hs.80768 chloride channel 7 /FL=gb:AF224741.1" | 396.39 | 265.55 | -1.49 | -1.19 | "all, " | HEK293T_Expression Human_ChIP_chip Human_CRE_prediction |
Sample Description:
Primary culture of human pancreatic islet was treated with cAMP agonist forskolin
(FSK) and compared with control untreated samples. RNA was extracted using the
Qiagen RNeasy kit. Two control and two forskolin treated samples were analyzed.
Microarray Analysis:
Total RNA samples were labeled and hybridized by standard protocol to Affymetrix
GeneChip Human Genome U133A 2.0 Array. Array data was analyzed using the dChip
software with PM-MM models.
Guidelines for Choosing camp Induced Genes in this Data
Set:
The fold change (FC) value is positive for increased expression and negative
for decrease expression. There is also a lower bound of fold change (LFC), which
is a conservative estimation of the fold change with 90% confidence. For this
data set, if a gene was induced by FSK with LFC>=1.3, we consider it as a
good camp induced gene and therefore a potential CREB target.