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To quickly search the same gene in another data set, click the links from the last column. The locuslink number will be used as query.


No probe set Gene Name Accession LocusLink Symbol Alias Symbols Description CTRL FSK (FSK vs CTRL) FC (FSK vs CTRL) LFC Note Link
1 203836_s_at mitogen-activated protein kinase kinase kinase 5 D844764217MAP3K5 ASK1;MAPKKK5;MEKK5 "gb:D84476.1 /DB_XREF=gi:1805499 /FEA=FLmRNA /CNT=78 /TID=Hs.151988.0 /TIER=FL+Stack /STK=12 /UG=Hs.151988 /LL=4217 /UG_GENE=MAP3K5 /DEF=Homo sapiens mRNA for ASK1, complete cds. /PROD=ASK1 /FL=gb:U67156.1 gb:NM_005923.2 gb:D84476.1" 318.43 293.76 -1.08 -0.98 "all, " HEK293T_Expression Human_ChIP_chip Human_CRE_prediction
2 203837_at mitogen-activated protein kinase kinase kinase 5 NM_0059234217MAP3K5 ASK1;MAPKKK5;MEKK5 "gb:NM_005923.2 /DEF=Homo sapiens mitogen-activated protein kinase kinase kinase 5 (MAP3K5), mRNA. /FEA=mRNA /GEN=MAP3K5 /PROD=MAPERK kinase kinase 5 /DB_XREF=gi:6031181 /UG=Hs.151988 mitogen-activated protein kinase kinase kinase 5 /FL=gb:U67156.1 gb:D84476.1 gb:NM_005923.2" 539.66 481.64 -1.12 -0.98 "all, " HEK293T_Expression Human_ChIP_chip Human_CRE_prediction

Sample Description:
Primary culture of human pancreatic islet was treated with cAMP agonist forskolin (FSK) and compared with control untreated samples. RNA was extracted using the Qiagen RNeasy kit. Two control and two forskolin treated samples were analyzed.

Microarray Analysis:
Total RNA samples were labeled and hybridized by standard protocol to Affymetrix GeneChip Human Genome U133A 2.0 Array. Array data was analyzed using the dChip software with PM-MM models.

Guidelines for Choosing camp Induced Genes in this Data Set:
The fold change (FC) value is positive for increased expression and negative for decrease expression. There is also a lower bound of fold change (LFC), which is a conservative estimation of the fold change with 90% confidence. For this data set, if a gene was induced by FSK with LFC>=1.3, we consider it as a good camp induced gene and therefore a potential CREB target.