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No probe set Gene Name Accession LocusLink Symbol Alias Symbols Description CTRL FSK (FSK vs CTRL) FC (FSK vs CTRL) LFC Note Link
1 222046_at arsenate resistance protein ARS2 AI52389551593ARS2 ASR2 Consensus includes gb:AI523895 /FEA=EST /DB_XREF=gi:4438030 /DB_XREF=est:tg97g03.x1 /CLONE=IMAGE:2116756 /UG=Hs.111801 arsenate resistance protein ARS2 105.95 102.76 -1.03 -0.78 "all, " HEK293T_Expression Human_ChIP_chip Human_CRE_prediction
2 214127_s_at gb:H28020 /DB_XREF=gi:898373 /DB_XREF=yl63g07.s1 /CLONE=IMAGE:162972 /FEA=EST /CNT=27 /TID=Hs.111801.1 /TIER=Stack /STK=15 /UG=Hs.111801 /LL=51593 /UG_GENE=ARS2 /UG_TITLE=arsenate resistance protein ARS2 H2802051593ARS2 ASR2 gb:H28020 /DB_XREF=gi:898373 /DB_XREF=yl63g07.s1 /CLONE=IMAGE:162972 /FEA=EST /CNT=27 /TID=Hs.111801.1 /TIER=Stack /STK=15 /UG=Hs.111801 /LL=51593 /UG_GENE=ARS2 /UG_TITLE=arsenate resistance protein ARS2 108.45 90.2 -1.2 -0.78 "all, " HEK293T_Expression Human_ChIP_chip Human_CRE_prediction
3 201679_at arsenate resistance protein ARS2 BE64607651593ARS2 ASR2 Consensus includes gb:BE646076 /FEA=EST /DB_XREF=gi:9970376 /DB_XREF=est:7e92g12.x1 /CLONE=IMAGE:3292678 /UG=Hs.111801 arsenate resistance protein ARS2 /FL=gb:BC000082.1 gb:AF082871.1 gb:NM_015908.1 119.12 114.83 -1.04 -0.87 "all, " HEK293T_Expression Human_ChIP_chip Human_CRE_prediction
4 222047_s_at arsenate resistance protein ARS2 AI52389551593ARS2 ASR2 Consensus includes gb:AI523895 /FEA=EST /DB_XREF=gi:4438030 /DB_XREF=est:tg97g03.x1 /CLONE=IMAGE:2116756 /UG=Hs.111801 arsenate resistance protein ARS2 770.28 743.09 -1.04 -0.97 "all, " HEK293T_Expression Human_ChIP_chip Human_CRE_prediction
5 201680_x_at arsenate resistance protein ARS2 NM_01590851593ARS2 ASR2 "gb:NM_015908.1 /DB_XREF=gi:7706237 /GEN=ARS2 /FEA=FLmRNA /CNT=220 /TID=Hs.111801.0 /TIER=FL+Stack /STK=41 /UG=Hs.111801 /LL=51593 /DEF=Homo sapiens arsenate resistance protein ARS2 (ARS2), mRNA. /PROD=arsenate resistance protein ARS2 /FL=gb:NM_015908.1 gb:AF082871.1 gb:BC000082.1" 829.75 760.38 -1.09 -1.01 "all, " HEK293T_Expression Human_ChIP_chip Human_CRE_prediction

Sample Description:
Primary culture of human pancreatic islet was treated with cAMP agonist forskolin (FSK) and compared with control untreated samples. RNA was extracted using the Qiagen RNeasy kit. Two control and two forskolin treated samples were analyzed.

Microarray Analysis:
Total RNA samples were labeled and hybridized by standard protocol to Affymetrix GeneChip Human Genome U133A 2.0 Array. Array data was analyzed using the dChip software with PM-MM models.

Guidelines for Choosing camp Induced Genes in this Data Set:
The fold change (FC) value is positive for increased expression and negative for decrease expression. There is also a lower bound of fold change (LFC), which is a conservative estimation of the fold change with 90% confidence. For this data set, if a gene was induced by FSK with LFC>=1.3, we consider it as a good camp induced gene and therefore a potential CREB target.