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No probe set Gene Name Accession LocusLink Symbol Alias Symbols Description CTRL FSK (FSK vs CTRL) FC (FSK vs CTRL) LFC Note Link
1 222211_x_at "Consensus includes gb:AF244812 /DEF=Homo sapiens SCAN domain-containing protein 2 (SCAND2) gene, complete cds, alternatively spliced /FEA=mRNA_2 /DB_XREF=gi:11345047 /UG=Hs.283825 SCAN domain-containing 2" AF24481254581SCAND2  "Consensus includes gb:AF244812 /DEF=Homo sapiens SCAN domain-containing protein 2 (SCAND2) gene, complete cds, alternatively spliced /FEA=mRNA_2 /DB_XREF=gi:11345047 /UG=Hs.283825 SCAN domain-containing 2" 439.41 487.12 1.11 0.97 "all, " HEK293T_Expression Human_ChIP_chip Human_CRE_prediction
2 206021_at SCAN domain containing 2 NM_02205054581SCAND2  "gb:NM_022050.1 /DB_XREF=gi:11545754 /GEN=SCAND2 /FEA=FLmRNA /CNT=20 /TID=Hs.283825.0 /TIER=FL /STK=0 /UG=Hs.283825 /LL=54581 /DEF=Homo sapiens SCAN domain-containing 2 (SCAND2), mRNA. /PROD=SCAN domain-containing 2 /FL=gb:NM_022050.1 gb:AF229246.1" 102.52 110.45 1.08 0.85 "all, " HEK293T_Expression Human_ChIP_chip Human_CRE_prediction
3 222177_s_at SCAN domain containing 2 AF24481254581SCAND2  "Consensus includes gb:AF244812 /DEF=Homo sapiens SCAN domain-containing protein 2 (SCAND2) gene, complete cds, alternatively spliced /FEA=mRNA_4 /DB_XREF=gi:11345047 /UG=Hs.283825 SCAN domain-containing 2" 80.96 75.75 -1.07 -0.84 "all, " HEK293T_Expression Human_ChIP_chip Human_CRE_prediction
4 215670_s_at SCAN domain containing 2 AK02284454581SCAND2  "Consensus includes gb:AK022844.1 /DEF=Homo sapiens cDNA FLJ12782 fis, clone NT2RP2001869, moderately similar to ZINC FINGER PROTEIN 191. /FEA=mRNA /DB_XREF=gi:10434472 /UG=Hs.321696 Homo sapiens cDNA FLJ12782 fis, clone NT2RP2001869, moderately similar to ZINC FINGER PROTEIN 191" 593.4 471.18 -1.26 -1.1 "all, " HEK293T_Expression Human_ChIP_chip Human_CRE_prediction

Sample Description:
Primary culture of human pancreatic islet was treated with cAMP agonist forskolin (FSK) and compared with control untreated samples. RNA was extracted using the Qiagen RNeasy kit. Two control and two forskolin treated samples were analyzed.

Microarray Analysis:
Total RNA samples were labeled and hybridized by standard protocol to Affymetrix GeneChip Human Genome U133A 2.0 Array. Array data was analyzed using the dChip software with PM-MM models.

Guidelines for Choosing camp Induced Genes in this Data Set:
The fold change (FC) value is positive for increased expression and negative for decrease expression. There is also a lower bound of fold change (LFC), which is a conservative estimation of the fold change with 90% confidence. For this data set, if a gene was induced by FSK with LFC>=1.3, we consider it as a good camp induced gene and therefore a potential CREB target.