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No probe set Gene Name Accession LocusLink Symbol Alias Symbols Description CTRL FSK (FSK vs CTRL) FC (FSK vs CTRL) LFC Note Link
1 214177_s_at pre-B-cell leukemia transcription factor interacting protein 1 AI93516257326PBXIP1 HPIP Consensus includes gb:AI935162 /FEA=EST /DB_XREF=gi:5674032 /DB_XREF=est:wp14e01.x1 /CLONE=IMAGE:2464824 /UG=Hs.8068 hematopoietic PBX-interacting protein 1266.96 1279.93 1.01 0.92 "all, " HEK293T_Expression Human_ChIP_chip Human_CRE_prediction
2 214176_s_at gb:AI348545 /DB_XREF=gi:4085751 /DB_XREF=qo34h12.x1 /CLONE=IMAGE:1910471 /FEA=EST /CNT=15 /TID=Hs.8068.2 /TIER=Stack /STK=8 /UG=Hs.8068 /LL=57326 /UG_GENE=HPIP /UG_TITLE=hematopoietic PBX-interacting protein AI34854557326PBXIP1 HPIP gb:AI348545 /DB_XREF=gi:4085751 /DB_XREF=qo34h12.x1 /CLONE=IMAGE:1910471 /FEA=EST /CNT=15 /TID=Hs.8068.2 /TIER=Stack /STK=8 /UG=Hs.8068 /LL=57326 /UG_GENE=HPIP /UG_TITLE=hematopoietic PBX-interacting protein 252 242.64 -1.04 -0.88 "all, " HEK293T_Expression Human_ChIP_chip Human_CRE_prediction
3 207838_x_at pre-B-cell leukemia transcription factor interacting protein 1 NM_02052457326PBXIP1 HPIP "gb:NM_020524.1 /DB_XREF=gi:10092622 /GEN=HPIP /FEA=FLmRNA /CNT=4 /TID=Hs.8068.0 /TIER=FL /STK=0 /UG=Hs.8068 /LL=57326 /DEF=Homo sapiens hematopoietic PBX-interacting protein (HPIP), mRNA. /PROD=hematopoietic PBX-interacting protein /FL=gb:NM_020524.1 gb:AF221521.1" 347.77 283.14 -1.23 -0.89 "all, " HEK293T_Expression Human_ChIP_chip Human_CRE_prediction
4 212259_s_at pre-B-cell leukemia transcription factor interacting protein 1 BF34426557326PBXIP1 HPIP gb:BF344265 /DB_XREF=gi:11291478 /DB_XREF=602017327F1 /CLONE=IMAGE:4152943 /FEA=mRNA /CNT=150 /TID=Hs.8068.1 /TIER=Stack /STK=13 /UG=Hs.8068 /LL=57326 /UG_GENE=HPIP /UG_TITLE=hematopoietic PBX-interacting protein 524.76 460.55 -1.14 -0.98 "all, " HEK293T_Expression Human_ChIP_chip Human_CRE_prediction

Sample Description:
Primary culture of human pancreatic islet was treated with cAMP agonist forskolin (FSK) and compared with control untreated samples. RNA was extracted using the Qiagen RNeasy kit. Two control and two forskolin treated samples were analyzed.

Microarray Analysis:
Total RNA samples were labeled and hybridized by standard protocol to Affymetrix GeneChip Human Genome U133A 2.0 Array. Array data was analyzed using the dChip software with PM-MM models.

Guidelines for Choosing camp Induced Genes in this Data Set:
The fold change (FC) value is positive for increased expression and negative for decrease expression. There is also a lower bound of fold change (LFC), which is a conservative estimation of the fold change with 90% confidence. For this data set, if a gene was induced by FSK with LFC>=1.3, we consider it as a good camp induced gene and therefore a potential CREB target.