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No probe set Gene Name Accession LocusLink Symbol Alias Symbols Description CTRL FSK (FSK vs CTRL) FC (FSK vs CTRL) LFC Note Link
1 214443_at poliovirus receptor NM_0065055817PVR CD155;HVED;PVS;TAGE4 "Consensus includes gb:NM_006505.1 /DEF=Homo sapiens poliovirus receptor (PVR), mRNA. /FEA=CDS /GEN=PVR /PROD=poliovirus receptor /DB_XREF=gi:5729994 /UG=Hs.321018 poliovirus receptor /FL=gb:NM_006505.1" 236 300.43 1.27 1.13 "all, " HEK293T_Expression Human_ChIP_chip Human_CRE_prediction
2 214444_s_at poliovirus receptor NM_0065055817PVR CD155;HVED;PVS;TAGE4 "gb:NM_006505.1 /DB_XREF=gi:5729994 /GEN=PVR /FEA=FLmRNA /CNT=27 /TID=Hs.321018.0 /TIER=FL /STK=0 /UG=Hs.321018 /LL=5817 /DEF=Homo sapiens poliovirus receptor (PVR), mRNA. /PROD=poliovirus receptor /FL=gb:NM_006505.1" 285.83 293.58 1.03 0.87 "all, " HEK293T_Expression Human_ChIP_chip Human_CRE_prediction
3 216283_s_at poliovirus receptor X641165817PVR CD155;HVED;PVS;TAGE4 Consensus includes gb:X64116 /DEF=H.sapiens PVR gene for poliovirus receptor (exon 1) /FEA=CDS_3 /DB_XREF=gi:35809 /UG=Hs.321018 poliovirus receptor 242.97 250.21 1.03 0.85 "all, " HEK293T_Expression Human_ChIP_chip Human_CRE_prediction
4 212662_at poliovirus receptor BE6152775817PVR CD155;HVED;PVS;TAGE4 "gb:BE615277 /DB_XREF=gi:9896876 /DB_XREF=601280637F1 /CLONE=IMAGE:3622736 /FEA=mRNA /CNT=101 /TID=Hs.171844.0 /TIER=Stack /STK=33 /UG=Hs.171844 /UG_TITLE=Homo sapiens cDNA: FLJ22296 fis, clone HRC04468" 136.43 152.77 1.12 0.83 "all, " HEK293T_Expression Human_ChIP_chip Human_CRE_prediction
5 32699_s_at poliovirus receptor X641165817PVR CD155;HVED;PVS;TAGE4 " Cluster Incl. X64116:H.sapiens PVR gene for poliovirus receptor (exon 1) /cds=(205,1299) /gb=X64116 /gi=35809 /ug=Hs.171844 /len=1300 " 606.76 575.22 -1.05 -0.93 "all, " HEK293T_Expression Human_ChIP_chip Human_CRE_prediction

Sample Description:
Primary culture of human pancreatic islet was treated with cAMP agonist forskolin (FSK) and compared with control untreated samples. RNA was extracted using the Qiagen RNeasy kit. Two control and two forskolin treated samples were analyzed.

Microarray Analysis:
Total RNA samples were labeled and hybridized by standard protocol to Affymetrix GeneChip Human Genome U133A 2.0 Array. Array data was analyzed using the dChip software with PM-MM models.

Guidelines for Choosing camp Induced Genes in this Data Set:
The fold change (FC) value is positive for increased expression and negative for decrease expression. There is also a lower bound of fold change (LFC), which is a conservative estimation of the fold change with 90% confidence. For this data set, if a gene was induced by FSK with LFC>=1.3, we consider it as a good camp induced gene and therefore a potential CREB target.