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No probe set Gene Name Accession LocusLink Symbol Alias Symbols Description CTRL FSK (FSK vs CTRL) FC (FSK vs CTRL) LFC Note Link
1 209498_at Consensus includes gb:X16354.1 /DEF=Human mRNA for transmembrane carcinoembryonic antigen BGPa (formerly TM1-CEA). /FEA=mRNA /PROD=TM1-CEA preprotein /DB_XREF=gi:37197 /UG=Hs.50964 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) /FL=gb:J03858.1 X16354634CEACAM1 BGP;BGP1;BGPI;CD66;CD66A;CD66a Consensus includes gb:X16354.1 /DEF=Human mRNA for transmembrane carcinoembryonic antigen BGPa (formerly TM1-CEA). /FEA=mRNA /PROD=TM1-CEA preprotein /DB_XREF=gi:37197 /UG=Hs.50964 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) /FL=gb:J03858.1 182.9 173.2 -1.06 -0.76 "all, " HEK293T_Expression Human_ChIP_chip Human_CRE_prediction
2 206576_s_at carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) NM_001712634CEACAM1 BGP;BGP1;BGPI;CD66;CD66A;CD66a "gb:NM_001712.1 /DB_XREF=gi:4502404 /GEN=CEACAM1 /FEA=FLmRNA /CNT=13 /TID=Hs.50964.0 /TIER=FL /STK=0 /UG=Hs.50964 /LL=634 /DEF=Homo sapiens carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) (CEACAM1), mRNA. /PROD=carcinoembryonic antigen-related cell adhesionmolecule 1 (biliary glycoprotein) /FL=gb:NM_001712.1" 248.08 239.94 -1.03 -0.89 "all, " HEK293T_Expression Human_ChIP_chip Human_CRE_prediction
3 210610_at carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) M69176634CEACAM1 BGP;BGP1;BGPI;CD66;CD66A;CD66a "gb:M69176.1 /DB_XREF=gi:179434 /GEN=BGP /FEA=FLmRNA /CNT=5 /TID=Hs.50964.2 /TIER=FL /STK=2 /UG=Hs.50964 /LL=634 /DEF=Human biliary glycoprotein mRNA, complete cds. /PROD=biliary glycoprotein a /FL=gb:M69176.1" 256.04 222.18 -1.15 -0.94 "all, " HEK293T_Expression Human_ChIP_chip Human_CRE_prediction
4 211889_x_at "gb:D12502.1 /DB_XREF=gi:219494 /GEN=BGP /FEA=FLmRNA /CNT=2 /TID=Hs.50964.5 /TIER=FL /STK=0 /UG=Hs.50964 /LL=634 /DEF=Human mRNA for biliary glycoprotein, complete cds. /PROD=biliary glycoprotein /FL=gb:D12502.1" D12502634CEACAM1 BGP;BGP1;BGPI;CD66;CD66A;CD66a "gb:D12502.1 /DB_XREF=gi:219494 /GEN=BGP /FEA=FLmRNA /CNT=2 /TID=Hs.50964.5 /TIER=FL /STK=0 /UG=Hs.50964 /LL=634 /DEF=Human mRNA for biliary glycoprotein, complete cds. /PROD=biliary glycoprotein /FL=gb:D12502.1" 399.6 371.78 -1.07 -0.99 "all, " HEK293T_Expression Human_ChIP_chip Human_CRE_prediction
5 211883_x_at "gb:M76742.1 /DB_XREF=gi:179480 /GEN=BGPa /FEA=FLmRNA /CNT=1 /TID=Hs.50964.4 /TIER=FL /STK=0 /UG=Hs.50964 /LL=634 /DEF=Homo sapiens alternatively spliced biliary glycoprotein (BGPa) mRNA, complete cds. /PROD=biliary glycoprotein /FL=gb:M76742.1" M76742634CEACAM1 BGP;BGP1;BGPI;CD66;CD66A;CD66a "gb:M76742.1 /DB_XREF=gi:179480 /GEN=BGPa /FEA=FLmRNA /CNT=1 /TID=Hs.50964.4 /TIER=FL /STK=0 /UG=Hs.50964 /LL=634 /DEF=Homo sapiens alternatively spliced biliary glycoprotein (BGPa) mRNA, complete cds. /PROD=biliary glycoprotein /FL=gb:M76742.1" 1053.76 888.27 -1.19 -1.05 "all, " HEK293T_Expression Human_ChIP_chip Human_CRE_prediction

Sample Description:
Primary culture of human pancreatic islet was treated with cAMP agonist forskolin (FSK) and compared with control untreated samples. RNA was extracted using the Qiagen RNeasy kit. Two control and two forskolin treated samples were analyzed.

Microarray Analysis:
Total RNA samples were labeled and hybridized by standard protocol to Affymetrix GeneChip Human Genome U133A 2.0 Array. Array data was analyzed using the dChip software with PM-MM models.

Guidelines for Choosing camp Induced Genes in this Data Set:
The fold change (FC) value is positive for increased expression and negative for decrease expression. There is also a lower bound of fold change (LFC), which is a conservative estimation of the fold change with 90% confidence. For this data set, if a gene was induced by FSK with LFC>=1.3, we consider it as a good camp induced gene and therefore a potential CREB target.