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No probe set Gene Name Accession LocusLink Symbol Alias Symbols Description CTRL FSK (FSK vs CTRL) FC (FSK vs CTRL) LFC Note Link
1 212852_s_at "Sjogren syndrome antigen A2 (60kDa, ribonucleoprotein autoantigen SS-A/Ro)" AL5386016738SSA2  "gb:AL538601 /DB_XREF=gi:12867040 /DB_XREF=AL538601 /CLONE=CS0DF024YB05 (5 prime) /FEA=mRNA /CNT=74 /TID=Hs.554.2 /TIER=Stack /STK=20 /UG=Hs.554 /LL=6738 /UG_GENE=SSA2 /UG_TITLE=Sjogren syndrome antigen A2 (60kD, ribonucleoprotein autoantigen SS-ARo)" 575.87 634.68 1.1 0.97 "all, " HEK293T_Expression Human_ChIP_chip Human_CRE_prediction
2 207520_at "Sjogren syndrome antigen A2 (60kDa, ribonucleoprotein autoantigen SS-A/Ro)" BG4949406738SSA2  "gb:BG494940 /DB_XREF=gi:13456455 /DB_XREF=602540961F1 /CLONE=IMAGE:4671854 /FEA=FLmRNA /CNT=5 /TID=Hs.554.0 /TIER=ConsEnd /STK=0 /UG=Hs.554 /LL=6738 /UG_GENE=SSA2 /UG_TITLE=Sjogren syndrome antigen A2 (60kD, ribonucleoprotein autoantigen SS-ARo) /FL=gb:NM_004600.1 gb:J04137.1" 51.49 61.97 1.2 0.94 "all, " HEK293T_Expression Human_ChIP_chip Human_CRE_prediction
3 210438_x_at "Sjogren syndrome antigen A2 (60kDa, ribonucleoprotein autoantigen SS-A/Ro)" M250776738SSA2  "gb:M25077.1 /DEF=Human SS-ARo ribonucleoprotein autoantigen 60 kd subunit mRNA, complete cds. /FEA=mRNA /DB_XREF=gi:387656 /UG=Hs.554 Sjogren syndrome antigen A2 (60kD, ribonucleoprotein autoantigen SS-ARo) /FL=gb:M25077.1" 347.82 355.93 1.02 0.91 "all, " HEK293T_Expression Human_ChIP_chip Human_CRE_prediction
4 212839_s_at "Sjogren syndrome antigen A2 (60kDa, ribonucleoprotein autoantigen SS-A/Ro)" AK0240446738SSA2  "gb:AK024044.1 /DB_XREF=gi:10436311 /FEA=mRNA /CNT=74 /TID=Hs.554.2 /TIER=ConsEnd /STK=0 /UG=Hs.554 /LL=6738 /UG_GENE=SSA2 /UG_TITLE=Sjogren syndrome antigen A2 (60kD, ribonucleoprotein autoantigen SS-ARo) /DEF=Homo sapiens cDNA FLJ13982 fis, clone Y79AA1001711, highly similar to Human 60-kdal ribonucleoprotein (Ro) mRNA." 121.39 148.68 1.22 0.9 "all, " HEK293T_Expression Human_ChIP_chip Human_CRE_prediction

Sample Description:
Primary culture of human pancreatic islet was treated with cAMP agonist forskolin (FSK) and compared with control untreated samples. RNA was extracted using the Qiagen RNeasy kit. Two control and two forskolin treated samples were analyzed.

Microarray Analysis:
Total RNA samples were labeled and hybridized by standard protocol to Affymetrix GeneChip Human Genome U133A 2.0 Array. Array data was analyzed using the dChip software with PM-MM models.

Guidelines for Choosing camp Induced Genes in this Data Set:
The fold change (FC) value is positive for increased expression and negative for decrease expression. There is also a lower bound of fold change (LFC), which is a conservative estimation of the fold change with 90% confidence. For this data set, if a gene was induced by FSK with LFC>=1.3, we consider it as a good camp induced gene and therefore a potential CREB target.