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To quickly search the same gene in another data set, click the links from the last column. The locuslink number will be used as query.


No probe set Gene Name Accession LocusLink Symbol Alias Symbols Description CTRL FSK (FSK vs CTRL) FC (FSK vs CTRL) LFC Note Link
1 201897_s_at CDC28 protein kinase regulatory subunit 1B BC00142584722DDA3 MGC1780 "gb:NM_001826.1 /DEF=Homo sapiens CDC28 protein kinase 1 (CKS1), mRNA. /FEA=mRNA /GEN=CKS1 /PROD=CDC28 protein kinase 1 /DB_XREF=gi:4502856 /UG=Hs.77550 CDC28 protein kinase 1 /FL=gb:BC001425.1 gb:AF274941.1 gb:AF279897.1 gb:NM_001826.1" 505.75 514.43 1.02 0.85 "all, " HEK293T_Expression Human_ChIP_chip Human_CRE_prediction
2 201896_s_at differential display and activated by p53 BC00142584722DDA3 MGC1780 "gb:BC001425.1 /DEF=Homo sapiens, Similar to differential display and activated by p53, clone MGC:1780, mRNA, complete cds. /FEA=mRNA /PROD=Similar to differential display and activated byp53 /DB_XREF=gi:12655140 /UG=Hs.77550 CDC28 protein kinase 1 /FL=gb:BC001425.1 gb:AF274941.1 gb:AF279897.1 gb:NM_001826.1" 346.35 302.91 -1.14 -1.02 "all, " HEK293T_Expression Human_ChIP_chip Human_CRE_prediction

Sample Description:
Primary culture of human pancreatic islet was treated with cAMP agonist forskolin (FSK) and compared with control untreated samples. RNA was extracted using the Qiagen RNeasy kit. Two control and two forskolin treated samples were analyzed.

Microarray Analysis:
Total RNA samples were labeled and hybridized by standard protocol to Affymetrix GeneChip Human Genome U133A 2.0 Array. Array data was analyzed using the dChip software with PM-MM models.

Guidelines for Choosing camp Induced Genes in this Data Set:
The fold change (FC) value is positive for increased expression and negative for decrease expression. There is also a lower bound of fold change (LFC), which is a conservative estimation of the fold change with 90% confidence. For this data set, if a gene was induced by FSK with LFC>=1.3, we consider it as a good camp induced gene and therefore a potential CREB target.