Search results are listed below.
Tip: To
quickly search the same gene in another data set, click the links from the last
column. The locuslink number will be used as query.
No | probe set | Gene Name | Accession | LocusLink | Symbol | Alias Symbols | Description | CTRL | FSK | (FSK vs CTRL) FC | (FSK vs CTRL) LFC | Note | Link |
1 | 210648_x_at | sorting nexin 3 | AB047360 | 8724 | SNX3 | MGC17570;SDP3;SNX3A | "gb:AB047360.1 /DB_XREF=gi:12957159 /GEN=SNX 3A /FEA=FLmRNA /CNT=3 /TID=Hs.12102.1 /TIER=FL /STK=0 /UG=Hs.12102 /LL=8724 /DEF=Homo sapiens SNX 3A mRNA for sorting nexin 3A, complete cds. /PROD=sorting nexin 3A /FL=gb:AB047360.1" | 2738.03 | 2886.08 | 1.05 | 1.01 | "all, " | HEK293T_Expression Human_ChIP_chip Human_CRE_prediction |
2 | 213545_x_at | sorting nexin 3 | BE962615 | 8724 | SNX3 | MGC17570;SDP3;SNX3A | gb:BE962615 /DB_XREF=gi:11765691 /DB_XREF=601655968R1 /CLONE=IMAGE:3855785 /FEA=EST /CNT=30 /TID=Hs.12102.2 /TIER=Stack /STK=19 /UG=Hs.12102 /LL=8724 /UG_GENE=SNX3 /UG_TITLE=sorting nexin 3 | 1513.52 | 1636.86 | 1.08 | 1.01 | "all, " | HEK293T_Expression Human_ChIP_chip Human_CRE_prediction |
3 | 200067_x_at | "Consensus includes gb:AL078596 /DEF=Human DNA sequence from clone RP3-429G5 on chromosome 6q21-22.1. Contains the NR2E1 gene for nuclear receptor 2E1 (tailless, TLL, TLX, XTLL), the 3 end of the SNX3 gene for sorting nexin 3, ESTs, STSs, GSSs and four predicted CpG islands /FEA=mRNA_2 /DB_XREF=gi:6010168 /UG=Hs.12102 sorting nexin 3 /FL=gb:AF062483.1 gb:AF034546.1 gb:NM_003795.1" | AL078596 | 8724 | SNX3 | MGC17570;SDP3;SNX3A | "Consensus includes gb:AL078596 /DEF=Human DNA sequence from clone RP3-429G5 on chromosome 6q21-22.1. Contains the NR2E1 gene for nuclear receptor 2E1 (tailless, TLL, TLX, XTLL), the 3 end of the SNX3 gene for sorting nexin 3, ESTs, STSs, GSSs and four predicted CpG islands /FEA=mRNA_2 /DB_XREF=gi:6010168 /UG=Hs.12102 sorting nexin 3 /FL=gb:AF062483.1 gb:AF034546.1 gb:NM_003795.1" | 1711.56 | 1810.93 | 1.06 | 1 | "all, " | HEK293T_Expression Human_ChIP_chip Human_CRE_prediction |
4 | 208781_x_at | sorting nexin 3 | AL078596 | 8724 | SNX3 | MGC17570;SDP3;SNX3A | "gb:AF062483.1 /DEF=Homo sapiens SDP3 mRNA, complete cds. /FEA=mRNA /PROD=SDP3 /DB_XREF=gi:3126978 /UG=Hs.12102 sorting nexin 3 /FL=gb:AF062483.1 gb:AF034546.1 gb:NM_003795.1" | 1693.17 | 1686.3 | -1 | -0.94 | "all, " | HEK293T_Expression Human_ChIP_chip Human_CRE_prediction |
Sample Description:
Primary culture of human pancreatic islet was treated with cAMP agonist forskolin
(FSK) and compared with control untreated samples. RNA was extracted using the
Qiagen RNeasy kit. Two control and two forskolin treated samples were analyzed.
Microarray Analysis:
Total RNA samples were labeled and hybridized by standard protocol to Affymetrix
GeneChip Human Genome U133A 2.0 Array. Array data was analyzed using the dChip
software with PM-MM models.
Guidelines for Choosing camp Induced Genes in this Data
Set:
The fold change (FC) value is positive for increased expression and negative
for decrease expression. There is also a lower bound of fold change (LFC), which
is a conservative estimation of the fold change with 90% confidence. For this
data set, if a gene was induced by FSK with LFC>=1.3, we consider it as a
good camp induced gene and therefore a potential CREB target.